Weiguo Fang
Research Associate

E-mail: wfang1@umd.edu
Phone: 301-405-5404
Fax: 301-314-9290
Web: www.stlegerlab.umd.edu
Mail: Department of Entomology * 4112 Plant Sciences Building * University of Maryland * College Park, MD 20742-4454
 
 
Research Interests
Pathogenesis and conidiation of Metarhizium anisopliae; Mosquito and malaria control with entomopathogenic fungi
 
 
Education
Ph.D. (2003) Southwest Agricultural University, Chongqing ChinaB. Sc (1997) Southwest Agricultural University, Chongqing China
 
 
Representative Publications
Copyright Notice:This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
 

Fang W, Vega-Rodriguez J, Ghosh AK, Jacobs-Loreana M, Kang A, St. Leger RJ. Development of transgenic fungi that kill human malaria parasites in mosquitoes. Science (accepted).

 

Gao Q, Jin K,....Fang W...St. Leger RJ, Wang C. Genome Sequencing and Comparative Transcriptomics of the Model Entomopathogenic Fungi Metarhizium anisopliae and M. acridum. PLoS Genet 7(1): e1001264. doi:10.1371/journal.pgen.1001264

 

Pava-Ripoll M, Angelini C, Fang W, Wang S, Posada F, St Leger RJ. The rhizosphere competent entomopathogen Metarhizium anisopliae expresses a specific subset of genes in plant root exudate. Microbiology. 2010 Oct 14. [Epub ahead of print]
 

Fang W, St. Leger RJ. Mrt, a Gene Unique to Fungi, Encodes an Oligosaccharide Transporter and Facilitates Rhizosphere Competency in Metarhizium robertsii. Plant Physiology Preview. Published on September 13, 2010, as DOI:10.1104/pp.110.163014



 

Fang W, Fernandes EK, Roberts DW, Bidochka MJ, St Leger RJ. A laccase exclusively expressed by Metarhizium anisopliae during isotropic growth is involved in pigmentation, tolerance to abiotic stresses and virulence. Fungal Genet Biol. 2010 Jul;47(7):602-7.


 

Fang W, St Leger RJ. RNA binding proteins mediate the ability of a fungus to adapt to the cold. Environ Microbiol. 2010 Mar;12(3):810-20.
 

Jin K, Zhang Y, Fang W, Luo Z, Zhou Y, Pei Y. Carboxylate transporter gene JEN1 from the entomopathogenic fungus Beauveria bassiana is involved in conidiation and virulence. Appl Environ Microbiol. 2010 Jan;76(1):254-63
 

Fang W, Feng J, Fan Y, Zhang Y, Bidochka MJ, Leger RJ, Pei Y.Expressing a fusion protein with protease and chitinase activities increases the virulence of the insect pathogen Beauveria bassiana.J Invertebr Pathol. 2009 Oct;102(2):155-9.
 

Wang S, Leclerque A, Pava-Ripoll M, Fang W, St Leger RJ. Comparative genomics using microarrays reveals divergence and loss of virulence-associated genes in host-specific strains of the insect pathogen Metarhizium anisopliae.Eukaryot Cell. 2009 Jun;8(6):888-98
 

Zhang Y, Zhao J, Fang W, Zhang J, Luo Z, Zhang M, Fan Y, Pei Y.Bbhog1, a MAP Kinase in the Entomopathogenic Fungus Beauveria bassiana, Is Involved in Response to Environmental Stress and Virulence to Insect.Appl Environ Microbiol. 2009 75(11):3787-95.
 

Fang W, Pava-Ripoll M, Wang S, St Leger R.Protein kinase A regulates production of virulence determinants by the entomopathogenic fungus, Metarhizium anisopliae.Fungal Genet Biol. 2009, 46:277-285
 

Liao X, Fang W, et al. Characterization of a Highly Active Promoter, PBbgpd, in Beauveria bassiana. Current Microbiology. 2008, 57:121-126
 

Fang W, Scully L,Zhang L,Pei Y & Bidochka MJ. Implication ofa regulatorofGprotein signalling(BbRGS1) in conidiationand conidial thermotolerance of the insect pathogenic fungus Beauveria bassiana.FEMS Microbiol Lett 2008 279:146–156.
 

Fang W, Pei Y, Bidochka MJ. A regulator of a G protein signalling (RGS) gene, cag8, from the insect-pathogenic fungus Metarhizium anisopliae is involved in conidiation, virulence and hydrophobin synthesis.Microbiology. 2007 Apr;153(Pt 4):1017-25.
 

Fan Y, Fang W, Xiao Y, Yang X, Zhang Y, Bidochka MJ, Pei Y. Directed evolution for increased chitinase activity.Appl Microbiol Biotechnol. 2007 Aug;76(1):135-139.
 

Fan Y*, Fang W*, Guo S, Pei X, Zhang Y, Xiao Y, Li D, Jin K, Bidochka MJ, Pei Y. Increased insect virulence in Beauveria bassiana strains overexpressing an engineered chitinase.Appl Environ Microbiol. 2007 Jan;73(1):295-302. *: equally contribute to this article
 

Fang W, Bidochka MJ. Expression of genes involved in germination, conidiogenesis and pathogenesis in Metarhizium anisopliae using quantitative real-time RT-PCR.Mycol Res. 2006 Oct;110(Pt 10):1165-71.
 

Fang W, Pei Y, Bidochka MJ. Transformation of Metarhizium anisopliae mediated by Agrobacterium tumefaciens.Can J Microbiol. 2006 Jul;52(7):623-6.
 

Yang X, Li J, Wang X, Fang W, Bidochka MJ, She R, Xiao Y, Pei Y. Psc-AFP, an antifungal protein with trypsin inhibitor activity from Psoralea corylifolia seeds.Peptides. 2006 Jul;27(7):1726-31.
 

Fang W, Leng B, Xiao Y, Jin K, Ma J, Fan Y, Feng J, Yang X, Zhang Y, Pei Y. Cloning of Beauveria bassiana chitinase gene Bbchit1 and its application to improve fungal strain virulence.Appl Environ Microbiol. 2005 Jan;71(1):363-70.
 

Fang W, Zhang Y, Yang X, Zheng X, Duan H, Li Y, Pei Y. Agrobacterium tumefaciens-mediated transformation of Beauveria bassiana using an herbicide resistance gene as a selection marker.J Invertebr Pathol. 2004 Jan;85(1):18-24.
 



 

 

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